Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ATAD3A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| ds-db4a006ea647 | provides_data_for | dataset | 1.00 |
| PD-L1 mitochondrial distribution | prevents | process | 0.95 |
| Cholesterol Metabolism | regulates | pathway | 0.95 |
| Alzheimer'S Disease | contributes_to | disease | 0.95 |
| PINK1 | inhibits | protein | 0.90 |
| triple-negative breast cancer resistance to ICI plus paclitaxel | promotes | phenotype | 0.90 |
| CYP46A1 | inhibits | gene | 0.90 |
| Cholesterol Accumulation | promotes | phenotype | 0.90 |
| mitophagy | inhibits | pathway | 0.90 |
| Alzheimer'S Disease | therapeutic_target | disease | 0.90 |
| App Processing | promotes | process | 0.85 |
| Synaptic Loss | promotes | phenotype | 0.85 |
| Cerebral ischemia-reperfusion injury | exacerbates | disease | 0.80 |
| CYP46A1 | activates | gene | 0.60 |
| PINK1 | activates | gene | 0.60 |
| TRIM25 | activates | gene | 0.60 |
| P62 | expressed_in | gene | 0.60 |
| PINK1 | expressed_in | gene | 0.60 |
| TRIM25 | expressed_in | gene | 0.60 |
| TRIM25 | regulates | gene | 0.60 |
| TRIM25 | interacts_with | gene | 0.60 |
| ubiquitin-proteasome | participates_in | pathway | 0.60 |
| autophagy pathway | participates_in | pathway | 0.60 |
| lipid metabolism | participates_in | pathway | 0.60 |
| neurons | expressed_in | cell_type | 0.55 |
| benchmark_ot_ad_answer_key:ATAD3A | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-db4a006ea647 | data_in | dataset | 1.00 |
| TRIM25 | modifies | protein | 0.95 |
| TRIM25 | associated_with | entity | 0.90 |
| paclitaxel | upregulates | drug | 0.85 |
| DA1 | targets | drug | 0.85 |
| APP | activates | gene | 0.60 |
| APP | inhibits | gene | 0.60 |
| benchmark_ot_ad_answer_key:ATAD3A | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||