concept

AUTOPHAGOSOME FORMATION

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about AUTOPHAGOSOME FORMATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

33Connections

0Hypotheses

0Analyses

3Outgoing

30Incoming

0Experiments

0Debates

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Pathway Diagram

graph TD
    AUTOPHAGOSOME_FORMATION["AUTOPHAGOSOME FORMATION"]
    AUTOPHAGOSOME_FORMATION -->|"involved_in"| ER_Mitochondria_Contact_Site["ER-Mitochondria Contact Site"]
    AUTOPHAGOSOME_FORMATION -->|"component_of"| Autophagy["Autophagy"]
    Autophagy -->|"involved_in"| AUTOPHAGOSOME_FORMATION
    ER_Mitochondria_Contact_Sites["ER-Mitochondria Contact Sites"] -->|"involved_in"| AUTOPHAGOSOME_FORMATION
    BECN1_PIK3C3_Complex["BECN1-PIK3C3 Complex"] -->|"involved_in"| AUTOPHAGOSOME_FORMATION
    Isolation_Membranes["Isolation Membranes"] -->|"involved_in"| AUTOPHAGOSOME_FORMATION
    LC3["LC3"] -->|"mediates"| AUTOPHAGOSOME_FORMATION
    MAP1LC3_Lipidation["MAP1LC3 Lipidation"] -->|"contributes to"| AUTOPHAGOSOME_FORMATION
    BECN1["BECN1"] -->|"involved_in"| AUTOPHAGOSOME_FORMATION

Outgoing (3)

Target	Relation	Type	Str
ER-Mitochondria Contact Site	involved_in	mechanism	0.95
Autophagy	component_of	process	0.90
ATG	associated_with	protein	0.90

Incoming (30)

Source	Relation	Type	Str
ER-mitochondria contact site	mediates	process	0.96
ER-Mitochondria Contact Sites	involved_in	organelle	0.95
Autophagy	involved_in	process	0.95
Map1Lc3	involved_in	protein	0.95
ATG14	involved_in	protein	0.93
ATG5	involved_in	protein	0.92
ATG2A-G433A	inhibits	variant	0.92
mitochondria-associated ER membrane	mediates	process	0.91
LC3	mediates	entity	0.90
BECN1-PIK3C3 Complex	involved_in	protein	0.90
ER-mitochondria contact sites	mediates	organelle	0.90
BECN1	activates	gene	0.90
SQSTM1	associated_with	protein	0.90
MAP1LC3 Lipidation	contributes_to	process	0.90
LC3	regulates	protein	0.90
BECN1	involved_in	gene	0.90
Isolation Membranes	involved_in	mechanism	0.90
RAB7A	promotes	protein	0.90
LC3B	biomarker_for	protein	0.90
ATG14	biomarker_for	protein	0.85
STX17	involved_in	protein	0.85
ATG9A	involved_in	protein	0.85
LRRK2	regulates	protein	0.80
ER-mitochondria contact sites	promotes	organelle	0.80
ACETYLATION	regulates	process	0.80
ULK1	activates	protein	0.70
ATG41	activates	protein	0.70
MAP1LC3B	part_of	gene	0.70
ATG9	activates	protein	0.70
BECN1	regulates	gene	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity