Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about cacna1f: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | CACNA1F |
| Full Name | Calcium Voltage-Gated Channel Auxiliary Subunit Alpha1F |
| Aliases | Page for CACNA1F Protein |
| Chromosome | Xp11.23 |
| Function | is located on chromosome Xp11.23 and encodes the alpha1F subunit of voltage-gated calcium channels, known as Cav1.4 |
| Primary Expression | retinal photoreceptors (both rods and cones) where it mediates the influx of calcium ions necessary for synaptic vesicle release and proper transmissi |
| Amino Acids | 166 aa |
| UniProt ID | [O43497](https://www.uniprot.org/uniprot/O43497) |
| Ensembl ID | ENSG00000102040 |
| GeneCards | CACNA1F |
| Human Protein Atlas | CACNA1F |
| Associated Diseases | neurodegeneration research |
| Interactions | CACNA1D, CACNA2D2, CACNA1I, CACNA2D1, CACNA1E, CACNA1H |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
CACNA1F["CACNA1F"]
CACNA1F -->|"contributes to"| CCS["CCS"]
CACNA1F -->|"interacts"| CACNA1D["CACNA1D"]
CACNA1F -->|"interacts"| CACNA2D2["CACNA2D2"]
CACNA1F -->|"interacts"| CACNA1I["CACNA1I"]
CACNA1F -->|"interacts"| CACNA2D1["CACNA2D1"]
CACNA1F -->|"interacts"| CACNA1E["CACNA1E"]
CACNA1F -->|"interacts"| CACNA1H["CACNA1H"]
CACNA1F -->|"interacts"| CACNA1G["CACNA1G"]
CCS -->|"contributes to"| CACNA1F
GAIN["GAIN"] -->|"contributes to"| CACNA1F| Target | Relation | Type | Str |
|---|---|---|---|
| CACNA1D | interacts_with | gene | 0.50 |
| CACNA2D2 | interacts_with | gene | 0.50 |
| CACNA1I | interacts_with | gene | 0.50 |
| CACNA2D1 | interacts_with | gene | 0.50 |
| CACNA1E | interacts_with | protein | 0.50 |
| CACNA1H | interacts_with | protein | 0.50 |
| CACNA1G | interacts_with | protein | 0.50 |
| CACNA1A | interacts_with | gene | 0.50 |
| CACNA1C | interacts_with | gene | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CACNA1A | associated_with | gene | 0.60 |
| CCS | contributes_to | gene | 0.60 |
| CACNA1C | associated_with | gene | 0.60 |
| CACNA2D2 | associated_with | gene | 0.60 |
| CACNA1G | associated_with | gene | 0.60 |
| CACNA1E | associated_with | gene | 0.60 |
| CACNA2D1 | associated_with | gene | 0.60 |
| GAIN | contributes_to | gene | 0.60 |
| CACNA1H | associated_with | gene | 0.60 |
| CACNA1I | associated_with | gene | 0.60 |
| CACNA1A | interacts_with | gene | 0.60 |
| CACNA1C | interacts_with | gene | 0.60 |
| CACNA1D | interacts_with | gene | 0.60 |
| CACNA1E | interacts_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| benchmark_ot_ad_answer_key:CACNA1F | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||