CLCN1

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLCN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CLCN1 is a gene implicated in neurodegeneration research. Key relationships include: associated with, regulates, interacts with. Connected to 17 entities in the SciDEX knowledge graph.

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graph TD
    CLCN1["<b>CLCN1</b>"]
    Muscle_excitability["Muscle excitability"]
    CLCN1 -->|"regulates"| Muscle_excitability
    Myotonia["Myotonia"]
    CLCN1 -->|"causes"| Myotonia
    CUGBP1["CUGBP1"]
    CLCN1 -->|"regulates"| CUGBP1
    GSK3_["GSK3beta"]
    CLCN1 -->|"interacts with"| GSK3_
    Manumycin_A["Manumycin A"]
    CLCN1 -->|"upregulates"| Manumycin_A
    NMD670["NMD670"]
    CLCN1 -->|"inhibits"| NMD670
    Hsp90_["Hsp90beta"]
    CLCN1 -->|"interacts with"| Hsp90_
    FKBP8["FKBP8"]
    CLCN1 -->|"interacts with"| FKBP8
    Neuromuscular_transmission["Neuromuscular transmission"]
    CLCN1 -->|"regulates"| Neuromuscular_transmission
    Muscle_weakness["Muscle weakness"]
    CLCN1 -->|"associated with"| Muscle_weakness
    CryAB["CryAB"]
    CLCN1 -->|"associated with"| CryAB
    Sp1["Sp1"]
    CLCN1 -->|"regulates"| Sp1
    style CLCN1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0