ESRRA

Understanding Entity Pages

This page aggregates everything SciDEX knows about ESRRA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

ESRRA is a gene implicated in neurodegeneration research. Key relationships include: activates, regulates, implicated in. Associated with Alzheimer's disease, Inflammation, neurodegenerative disease. Connected to 16 entities in the SciDEX knowledge graph.

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graph TD
    ESRRA["<b>ESRRA</b>"]
    DKK1["DKK1"]
    ESRRA -->|"regulates"| DKK1
    Alzheimer_s_disease{"Alzheimer's disease"}
    ESRRA -->|"associated with"| Alzheimer_s_disease
    neurodegenerative_disease{"neurodegenerative disease"}
    ESRRA -->|"regulates"| neurodegenerative_disease
    PTEN["PTEN"]
    ESRRA -->|"activates"| PTEN
    AUTOPHAGY["AUTOPHAGY"]
    ESRRA -->|"activates"| AUTOPHAGY
    PINK1["PINK1"]
    ESRRA -->|"activates"| PINK1
    ATG5["ATG5"]
    ESRRA -->|"activates"| ATG5
    Autophagy(["Autophagy"])
    ESRRA -->|"activates"| Autophagy
    Mitophagy(["Mitophagy"])
    ESRRA -->|"activates"| Mitophagy
    neurodegeneration["neurodegeneration"]
    ESRRA -->|"implicated in"| neurodegeneration
    MITOPHAGY["MITOPHAGY"]
    MITOPHAGY -->|"activates"| ESRRA
    style ESRRA fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0