concept

GMPR

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GMPR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

41Connections

0Hypotheses

0Analyses

25Outgoing

16Incoming

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💡 Concept Info

Name	GMPR
Key Genes/Proteins	AMPK, GSK3, AND, ALZHEIMER'S DISEASE, NPTX2, MET
Related Diseases	Alzheimer's Disease, Alzheimer
Related Pathways	Amyloid, Wnt, Tau Phosphorylation

Wiki Pages (1)

Knowledge base pages for this entity

IMPDH1 Gene - Inosine Monophosphate Dehydrogenase 1

gene · 754 words

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Pathway Diagram

graph TD
    GMPR["GMPR"]
    GMPR -.biomarker for.-> Alzheimer_s_Disease["Alzheimer's Disease"]
    GMPR -->|"modulates"| Tau_Phosphorylation["Tau Phosphorylation"]
    GMPR -->|"inhibits"| Alzheimer["Alzheimer"]
    GMPR -->|"phosphorylates"| AMPK["AMPK"]
    GMPR -->|"inhibits"| GSK3["GSK3"]
    GMPR -->|"inhibits"| AND["AND"]
    GMPR -->|"inhibits"| ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    GENES["GENES"] -->|"inhibits"| GMPR
    AMYLOID["AMYLOID"] -->|"inhibits"| GMPR
    WIF1["WIF1"] -->|"inhibits"| GMPR
    ALZHEIMER["ALZHEIMER"] -->|"inhibits"| GMPR
    WNT["WNT"] -->|"inhibits"| GMPR
    NPTX2["NPTX2"] -->|"target for"| GMPR

Outgoing (25)

Target	Relation	Type	Str
Alzheimer's Disease	biomarker_for	disease	0.90
Tau Phosphorylation	modulates	process	0.80
Alzheimer	inhibits	disease	0.65
Alzheimer	therapeutic_target	disease	0.65
AMPK	phosphorylates	gene	0.60
GSK3	inhibits	gene	0.60
AND	inhibits	gene	0.60
ALZHEIMER'S DISEASE	inhibits	gene	0.60
NPTX2	inhibits	gene	0.60
MET	inhibits	gene	0.60
TAU	phosphorylates	gene	0.60
Amyloid	inhibits	pathway	0.60
Wnt	inhibits	pathway	0.60
Tau Phosphorylation	phosphorylates	pathway	0.60
TAU	associated_with	gene	0.60
MET	therapeutic_target	gene	0.60
GSK3	therapeutic_target	gene	0.60
Wnt	therapeutic_target	pathway	0.60
WNT	inhibits	gene	0.60
AMYLOID	inhibits	gene	0.60
GENES	inhibits	gene	0.60
NPTX2	therapeutic_target	gene	0.60
App	inhibits	protein	0.60
Amyloid	therapeutic_target	protein	0.60
tau phosphorylation	interacts_with	process	0.60

Incoming (16)

Source	Relation	Type	Str
GENES	inhibits	gene	0.60
AMYLOID	inhibits	gene	0.60
WIF1	inhibits	gene	0.60
ALZHEIMER	inhibits	gene	0.60
WNT	inhibits	gene	0.60
AMPK	associated_with	gene	0.60
NPTX2	therapeutic_target	gene	0.60
WIF1	therapeutic_target	gene	0.60
WNT	therapeutic_target	gene	0.60
ALZHEIMER	therapeutic_target	gene	0.60
GSK3	inhibits	gene	0.60
ALZHEIMER'S DISEASE	inhibits	gene	0.60
GSK3	therapeutic_target	gene	0.60
MET	therapeutic_target	gene	0.60
TAU	associated_with	gene	0.60
AMPK	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found