Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GSPT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GSPT1 |
| Key Genes/Proteins | AND, GLIOBLASTOMA |
| Related Diseases | Glioblastoma, Als, Tumor, Cancer, ALS |
| Related Pathways | Mtor |
Knowledge base pages for this entity
graph TD
GSPT1["GSPT1"]
GSPT1 -->|"regulates"| Cellular_Functions["Cellular Functions"]
GSPT1 -->|"target for"| Glioblastoma["Glioblastoma"]
GSPT1 -->|"target for"| Als["Als"]
GSPT1 -->|"inhibits"| Tumor["Tumor"]
GSPT1 -->|"inhibits"| AND["AND"]
GSPT1 -->|"inhibits"| Mtor["Mtor"]
GSPT1 -->|"target for"| GLIOBLASTOMA["GLIOBLASTOMA"]
YB_3_17["YB-3-17"] -->|"degrades"| GSPT1
DDB1["DDB1"] -->|"binds"| GSPT1
MTOR["MTOR"] -->|"inhibits"| GSPT1
GLIOBLASTOMA -->|"target for"| GSPT1| Target | Relation | Type | Str |
|---|---|---|---|
| Glioblastoma | associated_with | disease | 0.90 |
| Therapeutic Target | biomarker_for | biomarker | 0.88 |
| Cellular Functions | regulates | process | 0.80 |
| Glioblastoma | therapeutic_target | disease | 0.65 |
| Als | therapeutic_target | disease | 0.65 |
| Tumor | inhibits | disease | 0.65 |
| Cancer | associated_with | disease | 0.65 |
| ALS | associated_with | disease | 0.65 |
| Glioblastoma | inhibits | disease | 0.65 |
| AND | inhibits | gene | 0.60 |
| Mtor | inhibits | pathway | 0.60 |
| GLIOBLASTOMA | therapeutic_target | gene | 0.60 |
| RNA | inhibits | gene | 0.60 |
| MTOR | inhibits | gene | 0.60 |
| GLIOBLASTOMA | inhibits | gene | 0.60 |
| glioblastoma | regulates | disease | 0.60 |
| glioblastoma | targets | disease | 0.60 |
| glioblastoma | inhibits | disease | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||