concept

GSPT1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GSPT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

24Connections
0Hypotheses
0Analyses
18Outgoing
6Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameGSPT1
Key Genes/ProteinsAND, GLIOBLASTOMA
Related DiseasesGlioblastoma, Als, Tumor, Cancer, ALS
Related PathwaysMtor

Wiki Pages (4)

Knowledge base pages for this entity

ubiquitin-proteasome-dysfunction-neurodegeneration

mechanism · 3548 words

Novel Therapeutic Modalities Synthesis

mechanism · 2284 words

Ubiquitin-Proteasome System Therapeutic Companies for Parkinson's Disease

company · 1660 words

Monte Rosa Therapeutics

company · 881 words

Pathway Diagram

graph TD
    GSPT1["GSPT1"]
    GSPT1 -->|"regulates"| Cellular_Functions["Cellular Functions"]
    GSPT1 -->|"target for"| Glioblastoma["Glioblastoma"]
    GSPT1 -->|"target for"| Als["Als"]
    GSPT1 -->|"inhibits"| Tumor["Tumor"]
    GSPT1 -->|"inhibits"| AND["AND"]
    GSPT1 -->|"inhibits"| Mtor["Mtor"]
    GSPT1 -->|"target for"| GLIOBLASTOMA["GLIOBLASTOMA"]
    YB_3_17["YB-3-17"] -->|"degrades"| GSPT1
    DDB1["DDB1"] -->|"binds"| GSPT1
    MTOR["MTOR"] -->|"inhibits"| GSPT1
    GLIOBLASTOMA -->|"target for"| GSPT1

Outgoing (18)

TargetRelationTypeStr
Glioblastomaassociated_withdisease0.90
Therapeutic Targetbiomarker_forbiomarker0.88
Cellular Functionsregulatesprocess0.80
Glioblastomatherapeutic_targetdisease0.65
Alstherapeutic_targetdisease0.65

Incoming (6)

SourceRelationTypeStr
YB-3-17degradescompound0.98
YB-3-17targetscompound0.95
DDB1bindsentity0.90
MTORinhibitsgene0.60
GLIOBLASTOMAtherapeutic_targetgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found