Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GALLIC ACID: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GALLIC ACID |
Knowledge base pages for this entity
graph TD
GALLIC_ACID["GALLIC ACID"]
GALLIC_ACID -->|"inhibits"| NF__B_MAPK_Signaling_Pathway["NF-kappaB/MAPK Signaling Pathway"]
GALLIC_ACID -->|"inhibits"| apoptosis["apoptosis"]
GALLIC_ACID -->|"inhibits"| NF_kappaB["NF-kappaB"]
GALLIC_ACID -->|"inhibits"| MAPK["MAPK"]
GALLIC_ACID -->|"downregulates"| IL_6["IL-6"]
GALLIC_ACID -->|"downregulates"| IL_1_["IL-1beta"]
GALLIC_ACID -->|"downregulates"| TNF__["TNF-alpha"]
GALLIC_ACID -->|"upregulates"| CLDN1["CLDN1"]| Target | Relation | Type | Str |
|---|---|---|---|
| NF-κB/MAPK Signaling Pathway | inhibits | pathway | 0.95 |
| Nf-Κb/Mapk Signaling Pathway | suppresses | pathway | 0.95 |
| BCL2 | associated_with | gene | 0.90 |
| BAX | associated_with | gene | 0.90 |
| NF-kappaB | inhibits | protein | 0.90 |
| IL6 | downregulates | gene | 0.90 |
| IL1B | downregulates | gene | 0.90 |
| TNF | downregulates | gene | 0.90 |
| Anti-Inflammatory | mediates | mechanism | 0.90 |
| Antioxidant Activity | mediates | mechanism | 0.90 |
| apoptosis | inhibits | phenotype | 0.90 |
| MAPK | inhibits | pathway | 0.90 |
| IL-6 | downregulates | protein | 0.90 |
| IL-1β | downregulates | protein | 0.90 |
| TNF-α | downregulates | protein | 0.90 |
| CLDN1 | upregulates | gene | 0.88 |
| OCLN | upregulates | gene | 0.88 |
| TJP1 | upregulates | gene | 0.88 |
| Apoptosis | inhibits | process | 0.87 |
| intestinal barrier dysfunction | prevents | phenotype | 0.85 |
| Intestinal Barrier Dysfunction | protects_against | phenotype | 0.85 |
| apoptosis | prevents | process | 0.85 |
| Inflammatory Bowel Disease | protects_against | disease | 0.85 |
| BAX | inhibits | gene | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||