concept

HPA AXIS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HPA AXIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections
0Hypotheses
0Analyses
9Outgoing
11Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameHPA AXIS

Wiki Pages (20)

Knowledge base pages for this entity

Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP)

therapeutic · 15794 words

Clinical Management Guide for CBS/PSP

therapeutic · 15224 words

cerebral-cortical-vasal-neurons

cell_type · 4639 words

protective-strategies-cbs-psp

therapeutic · 4501 words

Paraventricular Hypothalamic Nucleus (PVN) Neurons

cell · 4274 words

Pathway Diagram

graph TD
    HPA_AXIS["HPA AXIS"]
    HPA_AXIS -->|"involved_in"| Hypersexual_Disorder["Hypersexual Disorder"]
    HPA_AXIS -->|"component_of"| Gut_Brain_Axis["Gut-Brain Axis"]
    HPA_AXIS -->|"dysregulation_associated_with"| depression["depression"]
    HPA_AXIS -->|"modulates"| Sepsis_Associated_Encephalopat["Sepsis-Associated Encephalopathy"]
    HPA_AXIS -->|"implicated in"| Alzheimer_s_disease["Alzheimer's disease"]
    HPA_AXIS -->|"implicated in"| DEPRESSION["DEPRESSION"]
    Chronic_Stress["Chronic Stress"] -->|"activates"| HPA_AXIS
    METHYLATION["METHYLATION"] -->|"regulates"| HPA_AXIS
    CRH["CRH"] -->|"involved_in"| HPA_AXIS
    CRHBP["CRHBP"] -->|"involved_in"| HPA_AXIS
    CRHR1["CRHR1"] -->|"involved_in"| HPA_AXIS
    FKBP5["FKBP5"] -->|"involved_in"| HPA_AXIS
    gut_microbiota["gut microbiota"] -->|"modulates"| HPA_AXIS
    Ginsenoside_Rg1["Ginsenoside Rg1"] -->|"inhibits"| HPA_AXIS

Outgoing (9)

TargetRelationTypeStr
Hypersexual Disorderassociated_withdisease0.95
Hypersexual Disorderinvolved_indisease0.90
Gut-Brain Axiscomponent_ofpathway0.85
depressiondysregulation_associated_withdisease0.85
Sepsis-Associated Encephalopathymodulatesdisease0.85

Incoming (11)

SourceRelationTypeStr
Chronic Stressactivatesprocess0.95
CRHR2involved_ingene0.95
NR3C1involved_ingene0.95
METHYLATIONregulatesprocess0.90
CRHinvolved_ingene0.90

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found