concept

CRHBP

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CRHBP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

42Connections
0Hypotheses
0Analyses
25Outgoing
17Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameCRHBP
Key Genes/ProteinsFKBP5, CRH, DNA, JUN, TNF-ALPHA, NR3C1
Related DiseasesHypersexual Disorder, Depression, Addiction
Related PathwaysHpa Axis, DNA Methylation, Epigenetic

Wiki Pages (6)

Knowledge base pages for this entity

Bed Nucleus of Stria Terminalis in Stress

cell · 2026 words

Hypothalamic CRH Neurons

cell · 1579 words

Paraventricular Hypothalamic CRH Neurons

cell · 1139 words

Corticotropin-Releasing Hormone (CRH) Neurons

cell · 1087 words

Field of Cajal Neurons

cell · 800 words

Pathway Diagram

graph TD
    CRHBP["CRHBP"]
    CRHBP -->|"methylates"| Depression["Depression"]
    CRHBP -->|"methylates"| Addiction["Addiction"]
    CRHBP -->|"interacts"| FKBP5["FKBP5"]
    CRHBP -->|"interacts"| CRH["CRH"]
    CRHBP -->|"interacts"| NR3C1["NR3C1"]
    CRHBP -->|"interacts"| CRHR1["CRHR1"]
    CRHBP -->|"interacts"| AND["AND"]
    CRHBP -->|"interacts"| GENES["GENES"]
    DNA_Methylation["DNA Methylation"] -->|"regulates"| CRHBP
    GENES -->|"interacts"| CRHBP
    CRHR1 -->|"interacts"| CRHBP
    CRH -->|"interacts"| CRHBP
    NR3C1 -->|"interacts"| CRHBP
    AND -->|"interacts"| CRHBP
    TNF_ALPHA["TNF-ALPHA"] -->|"methylates"| CRHBP
    JUN["JUN"] -->|"methylates"| CRHBP

Outgoing (25)

TargetRelationTypeStr
Hpa Axisinvolved_inpathway0.90
Hypersexual Disorderassociated_withdisease0.80
Depressionassociated_withdisease0.65
Depressionmethylatesdisease0.65
Addictionmethylatesdisease0.65

Incoming (17)

SourceRelationTypeStr
DNA Methylationregulatesmechanism0.85
GENESinteracts_withgene0.60
DNAassociated_withgene0.60
TNFassociated_withgene0.60
CRHR1interacts_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found