protein

HTR2CPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HTR2CPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

0Debates

Summary

Htr2C Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	HTR2CPROTEIN
Protein Type	Receptor
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	the central nervous system and plays diverse roles in mood regulation, appetite, sleep, cognition, and motor control
Subcellular Localization	** \| Cell membrane, caveolin-rich domains \|
Molecular Weight	70 kDa
GeneCards	HTR2CPROTEIN
Human Protein Atlas	HTR2CPROTEIN
N-terminal tail	Short extracellular sequence
Loop regions	Connect transmembrane helices
Seven α-helices	Cross the lipid bilayer
Conserved motifs	For ligand binding and G protein coupling
Orthosteric binding site	In the transmembrane core
C-terminal tail	Long intracellular tail with multiple phosphorylation sites
RNA editing site	A site in the coding sequence (positions 156, 157, 158)
Associated Diseases	Alzheimer, Alzheimer's disease, Anxiety, Autism, Bipolar
Interactions	CACNA1B, CACNA1H, DRD1, DRD2, GABRA1, GABRB2
KG Connections	134 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

htr2c Protein

protein · 858 words

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Pathway Diagram

graph TD
    HTR2CPROTEIN["HTR2CPROTEIN"]
    neurodegeneration["neurodegeneration"]
    HTR2CPROTEIN -->|"implicated_in"| neurodegeneration
    style HTR2CPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning HTR2CPROTEIN in their description or question text

No additional research found