concept

IFI27L2A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IFI27L2A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

31Connections

0Hypotheses

0Analyses

18Outgoing

12Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	IFI27L2A
Key Genes/Proteins	INTERFERONS, STROKE
Related Diseases	Pro-inflammatory Phenotype, Ischemic Stroke, Neurodegeneration, Stroke, Aging

Pathway Diagram

graph TD
    IFI27L2A["IFI27L2A"]
    IFI27L2A -->|"regulates"| Microglial_Inflammation["Microglial Inflammation"]
    IFI27L2A -->|"expressed in"| Microglia["Microglia"]
    IFI27L2A -->|"activates"| Mitochondrial_ROS_Production["Mitochondrial ROS Production"]
    IFI27L2A -->|"involved_in"| Brain_Inflammation["Brain Inflammation"]
    IFI27L2A -.biomarker for.-> Aged_Brain["Aged Brain"]
    IFI27L2A -->|"activates"| Neurodegeneration["Neurodegeneration"]
    IFI27L2A -->|"regulates"| Stroke["Stroke"]
    IFI27L2A -->|"activates"| Aging["Aging"]
    Aging -->|"upregulates"| IFI27L2A
    Ischemic_Stroke["Ischemic Stroke"] -->|"upregulates"| IFI27L2A
    INTERFERONS["INTERFERONS"] -->|"upregulates"| IFI27L2A
    Pro_inflammatory_Molecules["Pro-inflammatory Molecules"] -->|"upregulates"| IFI27L2A
    AGING["AGING"] -->|"activates"| IFI27L2A
    NEURODEGENERATION["NEURODEGENERATION"] -->|"activates"| IFI27L2A
    INFLAMMATION["INFLAMMATION"] -->|"regulates"| IFI27L2A
    ROS["ROS"] -->|"activates"| IFI27L2A

Outgoing (19)

Target	Relation	Type	Str
Microglial Inflammation	regulates	process	0.95
Microglia	expressed_in	cell_type	0.95
Mitochondrial ROS Production	activates	process	0.90
Pro-inflammatory Phenotype	associated_with	phenotype	0.90
Brain Inflammation	involved_in	process	0.90
Neurodegeneration	associated_with	disease	0.75
Neurodegeneration	activates	disease	0.65
Stroke	regulates	disease	0.65
Aging	activates	disease	0.65
Inflammation	regulates	disease	0.65
STROKE	regulates	gene	0.60
MICROGLIA	activates	gene	0.60
RNA	regulates	gene	0.60
AGING	activates	gene	0.60
Microglia	activates	cell_type	0.60
AND	activates	gene	0.60
ROS	activates	gene	0.60
Interferon	activates	protein	0.60

Incoming (12)

Source	Relation	Type	Str
Aging	upregulates	process	0.90
Ischemic Stroke	upregulates	disease	0.90
INTERFERONS	upregulates	protein	0.85
Pro-inflammatory Molecules	upregulates	compound	0.85
AGING	activates	gene	0.60
NEURODEGENERATION	activates	gene	0.60
INFLAMMATION	regulates	gene	0.60
ROS	activates	gene	0.60
RNA	regulates	gene	0.60
AND	activates	gene	0.60
STROKE	regulates	gene	0.60
MICROGLIA	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found