protein

Interferon

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Interferon: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

557Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

No summary available yet. View on Wiki →

🔬 Protein Info

Gene Symbol	Interferon
Associated Diseases	Aging, Als, Alzheimer, Amyotrophic Lateral Sclerosis, Cancer, Encephalitis
Interactions	DISC1, GBA, TAX1BP1, ROS, ALS, PINK1
KG Connections	459 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    Interferon["Interferon"] -->|"interacts"| Dementia["Dementia"]
    style Dementia fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Interferon["Interferon"] -->|"interacts"| Alzheimer["Alzheimer"]
    style Alzheimer fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Interferon["Interferon"] -->|"interacts"| Frontotemporal_Dementia["Frontotemporal Dementia"]
    style Frontotemporal_Dementia fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Interferon["Interferon"] -->|"interacts"| Parkinson["Parkinson"]
    style Parkinson fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Interferon["Interferon"] -->|"interacts"| Als["Als"]
    style Als fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Interferon["Interferon"] -->|"activates"| Aging["Aging"]
    style Aging fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Interferon["Interferon"] -->|"associated"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    style Amyotrophic_Lateral_Sclerosis fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    HNRNPA1["HNRNPA1"] -->|"regulates"| Interferon["Interferon"]
    style HNRNPA1 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    DISC1["DISC1"] -->|"interacts"| Interferon["Interferon"]
    style DISC1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    GBA["GBA"] -->|"interacts"| Interferon["Interferon"]
    style GBA fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    TAX1BP1["TAX1BP1"] -->|"interacts"| Interferon["Interferon"]
    style TAX1BP1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    ROS["ROS"] -->|"interacts"| Interferon["Interferon"]
    style ROS fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    style Interferon fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (146)

Target	Relation	Type	Str
ZBP1	upregulates	protein	0.85
Dementia	interacts_with	disease	0.60
Alzheimer	interacts_with	disease	0.60
Frontotemporal Dementia	interacts_with	disease	0.60
Parkinson	interacts_with	disease	0.60
Als	interacts_with	disease	0.60
Aging	activates	disease	0.60
Amyotrophic Lateral Sclerosis	associated_with	disease	0.60
Als	associated_with	disease	0.60
Fibrosis	interacts_with	disease	0.60
Cancer	interacts_with	disease	0.60
Cancer	activates	disease	0.60
Ferroptosis	activates	disease	0.60
Als	activates	disease	0.60
Addiction	therapeutic_target	disease	0.60
Cancer	therapeutic_target	disease	0.60
Diabetes	activates	disease	0.60
Hypertension	activates	disease	0.60
Obesity	activates	disease	0.60
Neurodegeneration	regulates	disease	0.60
Alzheimer	regulates	disease	0.60
Als	regulates	disease	0.60
Alzheimer	associated_with	disease	0.60
Neurodegeneration	associated_with	disease	0.60
Multiple Sclerosis	associated_with	disease	0.60
Encephalitis	associated_with	disease	0.60
Neuroinflammation	associated_with	disease	0.60
Stroke	interacts_with	disease	0.60
Als	inhibits	disease	0.60
Neurodegeneration	activates	disease	0.60
Multiple Sclerosis	activates	disease	0.60
Cancer	associated_with	disease	0.60
Als	therapeutic_target	disease	0.60
Aging	expressed_in	disease	0.60
Als	expressed_in	disease	0.60
Atherosclerosis	activates	disease	0.60
Lymphoma	activates	disease	0.60
Alzheimer	therapeutic_target	disease	0.60
Neurodegeneration	therapeutic_target	disease	0.60
Multiple Sclerosis	therapeutic_target	disease	0.60
Amyotrophic Lateral Sclerosis	therapeutic_target	disease	0.60
Parkinson	therapeutic_target	disease	0.60
Huntington	therapeutic_target	disease	0.60
Neuroinflammation	therapeutic_target	disease	0.60
Parkinson	activates	disease	0.60
Neuroinflammation	activates	disease	0.60
Neurodegeneration	degrades	disease	0.60
Ferroptosis	degrades	disease	0.60
Multiple Sclerosis	degrades	disease	0.60
Aging	therapeutic_target	disease	0.60

Incoming (411)

Source	Relation	Type	Str
HNRNPA1	upregulates	protein	0.85
DISC1	interacts_with	gene	0.60
GBA	interacts_with	gene	0.60
TAX1BP1	interacts_with	gene	0.60
ROS	interacts_with	gene	0.60
ALS	interacts_with	gene	0.60
PINK1	interacts_with	gene	0.60
CTSD	interacts_with	gene	0.60
G3BP1	interacts_with	gene	0.60
BCL2L13	interacts_with	gene	0.60
RB1	interacts_with	gene	0.60
CANX	interacts_with	gene	0.60
PRKN	interacts_with	gene	0.60
ALZHEIMER	interacts_with	gene	0.60
AMPK	interacts_with	gene	0.60
DEMENTIA	interacts_with	gene	0.60
IFN	associated_with	gene	0.60
STING	activates	gene	0.60
MITOCHONDRIA	activates	gene	0.60
TDP-43	associated_with	gene	0.60
ALS	associated_with	gene	0.60
DNA	activates	gene	0.60
MTDNA	activates	gene	0.60
CGAS	activates	gene	0.60
RIPK1	interacts_with	gene	0.60
PPARG	interacts_with	gene	0.60
WNT	interacts_with	gene	0.60
TFEB	interacts_with	gene	0.60
CFTR	interacts_with	gene	0.60
RICTOR	interacts_with	gene	0.60
GRB2	interacts_with	gene	0.60
HSP70	interacts_with	gene	0.60
STAT3	interacts_with	gene	0.60
IFN	interacts_with	gene	0.60
DDIT3	interacts_with	gene	0.60
MLST8	interacts_with	gene	0.60
ANGPT1	activates	gene	0.60
PDGFRB	activates	gene	0.60
CD8	associated_with	gene	0.60
PD-1	activates	gene	0.60
PLA2G4A	inhibits	gene	0.60
PLA2G6	inhibits	gene	0.60
MTDNA	associated_with	gene	0.60
GPX4	associated_with	gene	0.60
ATG	associated_with	gene	0.60
POLG	associated_with	gene	0.60
NCOA4	associated_with	gene	0.60
ALOX	associated_with	gene	0.60
ATM	associated_with	gene	0.60
FERROPTOSIS	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Interferon

Understanding Entity Pages

Wiki Pages (20)

Novel Therapy Index

Microglia CD8+ T Cell Recruitment -- Supplementary WW Content

neuroinflammation

CLCN10 — Chloride Voltage-Gated Channel 10

Blood-Brain Barrier Dysfunction in Neurodegeneration

Vitamin D Signaling Pathway in Neurodegeneration

nlrc5-protein

proteasome-ubiquitin-system-dysfunction-parkinsons

Neuroinflammation-Mitochondria Crosstalk Pathway

DNA Damage Response Impairment Pathway

Multiple Sclerosis (MS)

Quinolinic Acid Neurotoxicity in Neurodegeneration

Neuroinflammation Across AD, PD, ALS, FTD, and HD

Tumor Necrosis Factor Alpha (TNF-α) as a Neurodegenerative Disease Biomarker

Neuroinflammation in Amyotrophic Lateral Sclerosis

JAK-STAT Signaling Pathway in Neurodegeneration

CBS/PSP Genetic Architecture

cGAS-STING Signaling in Parkinson's Disease