concept

IL17

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL17: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

24Connections
0Hypotheses
0Analyses
17Outgoing
7Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameIL17
Key Genes/ProteinsIL1B, IL6, TNF
Related DiseasesSkeletal Muscle Inflammation, rosacea, Cognitive Impairment

Wiki Pages (7)

Knowledge base pages for this entity

Psychobiotic Therapy for Neurodegenerative Diseases

mechanism · 3674 words

Adaptive Immunity in Neurodegeneration

mechanism · 3243 words

move-brain-pd-nct07299279

clinical_trial · 2892 words

IL-12 Protein

protein · 2116 words

IL23A Gene

gene · 2068 words

Pathway Diagram

graph TD
    IL17["IL17"]
    IL17 -->|"product_of"| Th17_Cell["Th17 Cell"]
    IL17 -->|"mediates"| Immune_Cell_Recruitment["Immune Cell Recruitment"]
    IL17 -->|"promotes"| Skeletal_Muscle_Inflammation["Skeletal Muscle Inflammation"]
    IL17 -->|"expressed in"| Neutrophils["Neutrophils"]
    IL17 -->|"expressed in"| Microglia["Microglia"]
    IL17 -->|"expressed in"| Neutrophil["Neutrophil"]
    IL17 -->|"upregulates"| IL1B["IL1B"]
    IL17 -->|"upregulates"| IL6["IL6"]
    Anti_Il_17_Antibody["Anti-Il-17 Antibody"] -->|"inhibits"| IL17
    Chemokines["Chemokines"] -->|"involved_in"| IL17
    MTOR["MTOR"] -->|"regulates"| IL17
    S100A9["S100A9"] -->|"activates"| IL17

Outgoing (17)

TargetRelationTypeStr
Th17 Cellproduct_ofcell_type0.95
Immune Cell Recruitmentmediatesprocess0.95
Skeletal Muscle Inflammationpromotesdisease0.95
Neutrophilsexpressed_incell_type0.90
Microgliaexpressed_incell_type0.90

Incoming (7)

SourceRelationTypeStr
Anti-Il-17 Antibodyinhibitsdrug0.95
Chemokinesinvolved_incompound0.80
MTORregulatesprotein0.70
SEPSISactivatesdisease0.65
S100A9activatesprotein0.64

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found