KIF13A

Understanding Entity Pages

This page aggregates everything SciDEX knows about KIF13A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

KIF13A is a monomeric kinesin-3 motor protein that mediates endocytic trafficking, synaptic vesicle transport, and APP processing in neurons. Implicated in Alzheimer's and Parkinson's disease.

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graph TD
    KIF13A["<b>KIF13A</b>"]
    Alzheimer{"Alzheimer"}
    KIF13A -->|"associated with"| Alzheimer
    Als{"Als"}
    KIF13A -->|"associated with"| Als
    Ms{"Ms"}
    KIF13A -->|"associated with"| Ms
    TRIM24["TRIM24"]
    KIF13A -->|"associated with"| TRIM24
    STX6["STX6"]
    KIF13A -->|"associated with"| STX6
    MAPT["MAPT"]
    KIF13A -->|"associated with"| MAPT
    neurodegeneration["neurodegeneration"]
    KIF13A -->|"implicated in"| neurodegeneration
    DUSP10["DUSP10"]
    DUSP10 -->|"associated with"| KIF13A
    MAP1S["MAP1S"]
    MAP1S -->|"associated with"| KIF13A
    PSP["PSP"]
    PSP -->|"associated with"| KIF13A
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"associated with"| KIF13A
    ASTROCYTES["ASTROCYTES"]
    ASTROCYTES -->|"associated with"| KIF13A
    SP1["SP1"]
    SP1 -->|"associated with"| KIF13A
    APOE["APOE"]
    APOE -->|"associated with"| KIF13A
    TAU["TAU"]
    TAU -->|"associated with"| KIF13A
    style KIF13A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0