Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LACTYLATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
LACTYLATION["LACTYLATION"]
LACTYLATION -->|"regulates"| MADD["MADD"]
LACTYLATION -->|"regulates"| inflammation["inflammation"]
LACTYLATION -->|"regulates"| angiogenesis["angiogenesis"]
LACTYLATION -->|"regulates"| lipid_metabolism_dysregulation["lipid metabolism dysregulation"]
LACTYLATION -->|"regulates"| coronary_heart_disease["coronary heart disease"]
LACTYLATION -->|"regulates"| cellular_metabolism["cellular metabolism"]
LACTYLATION -->|"regulates"| epigenetic_regulation["epigenetic regulation"]
LACTYLATION -->|"activates"| tissue_homeostasis["tissue homeostasis"]
lactate["lactate"] -->|"activates"| LACTYLATION| Target | Relation | Type | Str |
|---|---|---|---|
| MADD | regulates | protein | 0.92 |
| FTO | modulates | protein | 0.90 |
| CDK2 | regulates | protein | 0.75 |
| melanoma | associated_with | disease | 0.70 |
| hepatocellular carcinoma | associated_with | disease | 0.70 |
| myocardial infarction | associated_with | disease | 0.70 |
| angiogenesis | regulates | process | 0.70 |
| lipid metabolism dysregulation | regulates | process | 0.70 |
| coronary heart disease | regulates | disease | 0.70 |
| cellular metabolism | regulates | process | 0.70 |
| tissue homeostasis | activates | process | 0.70 |
| fibrosis | causes | disease | 0.70 |
| chronic inflammation | activates | process | 0.70 |
| metabolic reprogramming | regulates | process | 0.70 |
| ischemia-reperfusion injury | regulates | process | 0.70 |
| Alzheimer's disease | associated_with | disease | 0.70 |
| inflammation | associated_with | process | 0.70 |
| inflammation | regulates | process | 0.70 |
| epigenetic regulation | regulates | process | 0.70 |
| mitochondrial dysfunction | causes | process | 0.70 |
| Dementia | contributes_to | disease | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||