Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEURONAL ACTIVITY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEURONAL ACTIVITY |
Knowledge base pages for this entity
graph TD
NEURONAL_ACTIVITY["NEURONAL ACTIVITY"]
NEURONAL_ACTIVITY -->|"regulates"| PARVALBUMIN_INTERNEURONS["PARVALBUMIN INTERNEURONS"]
NEURONAL_ACTIVITY -->|"activates"| CREB["CREB"]
NEURONAL_ACTIVITY -->|"regulates"| Axonal_Regeneration["Axonal Regeneration"]
NEURONAL_ACTIVITY -->|"causes"| DNA_Breaks["DNA Breaks"]
NEURONAL_ACTIVITY -->|"modulates"| Neuroregeneration["Neuroregeneration"]
NEURONAL_ACTIVITY -->|"causes"| Programmed_DNA_Breaks["Programmed DNA Breaks"]
NEURONAL_ACTIVITY -->|"modulates"| GFAP["GFAP"]
Deschloroclozapine["Deschloroclozapine"] -->|"modulates"| NEURONAL_ACTIVITY
Dreadds["Dreadds"] -->|"modulates"| NEURONAL_ACTIVITY
A___["Aeta-alpha"] -->|"inhibits"| NEURONAL_ACTIVITY
Synaptic_Pruning["Synaptic Pruning"] -->|"regulates"| NEURONAL_ACTIVITY
MAPT["MAPT"] -->|"regulates"| NEURONAL_ACTIVITY| Target | Relation | Type | Str |
|---|---|---|---|
| Parvalbumin Interneuron Maturation | associated_with | process | 0.95 |
| PPARGC1A | activates | gene | 0.90 |
| PARVALBUMIN INTERNEURONS | regulates | entity | 0.90 |
| CREB | activates | protein | 0.88 |
| Axonal Regeneration | regulates | process | 0.85 |
| DNA Breaks | causes | mechanism | 0.85 |
| Circadian Function | associated_with | process | 0.85 |
| Neuroregeneration | modulates | process | 0.82 |
| Programmed DNA Breaks | causes | process | 0.80 |
| GFAP | modulates | gene | 0.80 |
| GFAP | regulates | gene | 0.80 |
| Neuroregeneration | regulates | process | 0.80 |
| BDNF | regulates | protein | 0.80 |
| Axonal Regeneration | modulates | process | 0.75 |
| NLGN3 | regulates | protein | 0.70 |
| NLGN3 | activates | protein | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Deschloroclozapine | modulates | compound | 0.95 |
| Dreadds | modulates | receptor | 0.95 |
| Astrocytes | modulates | cell_type | 0.92 |
| Aη-α | inhibits | compound | 0.90 |
| BDNF | modulates | protein | 0.90 |
| Chemogenetics | enables_control_of | technology | 0.90 |
| Synaptic Pruning | regulates | process | 0.85 |
| MAPT | regulates | gene | 0.85 |
| Functional Hyperemia | modulates | process | 0.80 |
| microglia | regulates | cell_type | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||