Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NONO: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | NONO |
| Full Name | Non-POU Domain Containing Octamer Binding |
| Chromosome | Xq13.1 |
| Protein Type | RNA-binding protein, DBHS family |
| Function | encodes a nuclear RNA-binding protein that belongs to the DBHS (Drosophila Behavior and Human Splicing) protein family. |
| Molecular Weight | 54 kDa |
| UniProt ID | [Q13435](https://www.uniprot.org/uniprot/Q13435) |
| Ensembl ID | ENSG00000147140 |
| OMIM | 300084 |
| GeneCards | NONO |
| Human Protein Atlas | NONO |
| Associated Diseases | neurodegeneration |
| Interactions | SQSTM1, FMR1, SND1, SFPQ, CANCER, RNA |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
NONO["<b>NONO</b>"]
Ms{"Ms"}
NONO -->|"interacts with"| Ms
Cancer{"Cancer"}
NONO -->|"interacts with"| Cancer
CANCER["CANCER"]
NONO -->|"interacts with"| CANCER
SQSTM1["SQSTM1"]
NONO -->|"interacts with"| SQSTM1
FMR1["FMR1"]
NONO -->|"interacts with"| FMR1
SND1["SND1"]
NONO -->|"interacts with"| SND1
neurodegeneration["neurodegeneration"]
NONO -->|"implicated in"| neurodegeneration
NPM1["NPM1"]
NPM1 -->|"interacts with"| NONO
G3BP1["G3BP1"]
G3BP1 -->|"interacts with"| NONO
style NONO fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||