gene 1,219 words KG: NONO 2026-03-24
kind:genesection:genesstate:published
Contents

NONO Gene

🧬 Gene Info
Gene SymbolNONO
Full NameNon-POU Domain Containing Octamer Binding
ChromosomeXq13.1
Protein TypeRNA-binding protein, DBHS family
Functionencodes a nuclear RNA-binding protein that belongs to the DBHS (Drosophila Behavior and Human Splicing) protein family.
Molecular Weight54 kDa
UniProt ID[Q13435](https://www.uniprot.org/uniprot/Q13435)
Ensembl IDENSG00000147140
OMIM300084
GeneCardsNONO
Human Protein AtlasNONO
Associated Diseasesneurodegeneration
InteractionsSQSTM1, FMR1, SND1, SFPQ, CANCER, RNA
KG Connections13 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (12)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Circadian-Synchronized Proteostasis Enhancement
Score: 0.58
Circadian Clock-Autophagy Synchronization
Score: 0.55
Phase-Separated Organelle Targeting
Score: 0.52
Temporal Decoupling via Circadian Clock Reset
Score: 0.52

Related Analyses (6)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived

See Also (6)

SQSTM1 — Sequestosome 1 (p62)
gene · KG edge: interacts_with
SND1 — Stonin 1
gene · KG edge: interacts_with
NPM1 Gene
gene · KG edge: interacts_with
G3BP1
gene · KG edge: interacts_with
FMR1 — Fragile X Messenger Ribonucleoprotein 1
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

NONO interacts_with SQSTM1
NONO interacts_with FMR1
NONO interacts_with SND1
NONO activates SFPQ
NONO interacts_with CANCER
NONO interacts_with Ms
NONO interacts_with Cancer
NONO activates RNA
NPM1 interacts_with NONO
G3BP1 interacts_with NONO