concept

OXPC

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about OXPC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections
2Hypotheses
1Analyses
11Outgoing
9Incoming
0Experiments

No summary available yet. View on Wiki →

💡 Concept Info
NameOXPC
Linked Hypotheses2 hypotheses

Wiki Pages (11)

Knowledge base pages for this entity

Munc18-1 Protein (STXBP1)

protein · 1223 words

Neurons in Lysosomal Storage Disorders with Neurodegeneration

cell · 1108 words

SCFD1

gene · 1061 words

Oxidative Stress in Neurodegeneration

mechanism · 997 words

sepsocs

gene · 957 words

Pathway Diagram

graph TD
    OXPC["OXPC"]
    OXPC -->|"causes"| SEPSOCS["SEPSOCS"]
    OXPC -->|"causes"| PFEN1["PFEN1"]
    OXPC -->|"causes"| neurons["neurons"]
    OXPC -->|"causes"| oligodendrocytes["oligodendrocytes"]
    OXPC -->|"activates"| PRDX2["PRDX2"]
    OXPC -->|"causes"| SCFD1["SCFD1"]
    OXPC -->|"activates"| MEF2A["MEF2A"]
    OXPC -->|"activates"| USF1["USF1"]
    GRPRPROTEIN["GRPRPROTEIN"] -->|"binds"| OXPC
    MUNC181PROTEIN["MUNC181PROTEIN"] -->|"binds"| OXPC

Outgoing (11)

TargetRelationTypeStr
Neurodegenerationcausesprocess0.95
SEPSOCScausesdisease0.90
Neuronsmediatescell_type0.90
Oligodendrocytesmediatescell_type0.90
PFEN1causesgene0.80

Incoming (9)

SourceRelationTypeStr
Microgliamodulatescell_type0.90
TREM2involved_ingene0.85
Oxidative Stresscausesprocess0.85
DCTN5associated_withgene0.80
GRPRPROTEINbindsreceptor0.80

Targeting Hypotheses (2)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
TREM2-SYK Signaling Axis Couples OxPC Recognition to Phagocy 0.505 neuroinflammation What molecular mechanisms enable microgl
Complement Cascade Activation Bridges Microglial OxPC Sensin 0.452 neuroinflammation What molecular mechanisms enable microgl

Mentioning Analyses (1)

Scientific analyses that reference this entity

What molecular mechanisms enable microglia to neutralize OxPC-mediated neurodege

neuroinflammation | 2026-04-13 | 2 hypotheses Top: 0.505

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found