PPARG

Understanding Entity Pages

This page aggregates everything SciDEX knows about PPARG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PPARG is a gene implicated in neurodegeneration research. Key relationships include: interacts with, regulates, activates. Associated with AD, ADH, ALS. Connected to 584 entities in the SciDEX knowledge graph.

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graph TD
    PPARG["PPARG"] -->|"Regulates"| fat_distribution["fat distribution"]
    PPARG["PPARG"] -->|"Regulates"| PPARGC1A["PPARGC1A"]
    PPARG["PPARG"] -->|"Encodes"| PPAR__["PPAR-gamma"]
    PPARG["PPARG"] -->|"Activates"| Metabolic_Syndrome["Metabolic Syndrome"]
    PPARG["PPARG"] -->|"Regulates"| Ischemia["Ischemia"]
    PPARG["PPARG"] -->|"Regulates"| Ms["Ms"]
    PPARG["PPARG"] -->|"Interacts With"| Cancer["Cancer"]
    PPARG["PPARG"] -->|"Interacts With"| Als["Als"]
    Abscisic_acid["Abscisic acid"] -->|"Activates"| PPARG["PPARG"]
    ACTB["ACTB"] -->|"Regulates"| PPARG["PPARG"]
    PPARA["PPARA"] -->|"Regulates"| PPARG["PPARG"]
    CAT["CAT"] -->|"Regulates"| PPARG["PPARG"]
    SQSTM1["SQSTM1"] -->|"Regulates"| PPARG["PPARG"]
    style PPARG fill:#8d4900,color:#e0e0e0
    style fat_distribution fill:#607D8B,color:#e0e0e0
    style PPARGC1A fill:#0d47a1,color:#e0e0e0
    style PPAR__ fill:#0d47a1,color:#e0e0e0
    style Metabolic_Syndrome fill:#b71c1c,color:#e0e0e0
    style Ischemia fill:#b71c1c,color:#e0e0e0
    style Ms fill:#b71c1c,color:#e0e0e0
    style Cancer fill:#b71c1c,color:#e0e0e0
    style Als fill:#b71c1c,color:#e0e0e0
    style Abscisic_acid fill:#00838f,color:#e0e0e0
    style ACTB fill:#8d4900,color:#e0e0e0
    style PPARA fill:#8d4900,color:#e0e0e0
    style CAT fill:#8d4900,color:#e0e0e0
    style SQSTM1 fill:#8d4900,color:#e0e0e0