Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SCAP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| SREBF | regulates | protein | 0.95 |
| SREBP2 | interacts_with | protein | 0.90 |
| Lysosomal Degradation | involved_in | process | 0.85 |
| Fatty Liver Disease | therapeutic_target | disease | 0.80 |
| STING | activates | gene | 0.70 |
| SREBF2 | interacts_with | gene | 0.60 |
| SREBF1 | activates | gene | 0.60 |
| SQSTM1 | associated_with | gene | 0.60 |
| SQSTM1 | interacts_with | gene | 0.60 |
| STING | associated_with | gene | 0.60 |
| STING | interacts_with | gene | 0.60 |
| SREBP2 | activates | gene | 0.60 |
| pyroptosis | participates_in | pathway | 0.60 |
| SREBP2 | regulates | gene | 0.60 |
| autophagy pathway | participates_in | pathway | 0.60 |
| SREBP2 | associated_with | gene | 0.60 |
| lipid metabolism | participates_in | pathway | 0.60 |
| oligodendrocytes | expressed_in | cell_type | 0.60 |
| macrophages | expressed_in | cell_type | 0.55 |
| benchmark_ot_ad_answer_key:SCAP | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| lycorine | interacts_with | drug | 0.90 |
| lycorine | inhibits | drug | 0.90 |
| SQSTM1 | interacts_with | protein | 0.90 |
| Lycorine | binds | compound | 0.90 |
| Lycorine | degrades | compound | 0.90 |
| Smaild Pathway | mediates | pathway | 0.80 |
| NLRP3 | activates | gene | 0.60 |
| NLRP3 | interacts_with | gene | 0.60 |
| NR1H3 | activates | gene | 0.60 |
| FAM134B | regulates | gene | 0.60 |
| FAM134B | activates | gene | 0.60 |
| INSIG1 | activates | gene | 0.60 |
| benchmark_ot_ad_answer_key:SCAP | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||