concept

VAV2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about VAV2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections
0Hypotheses
0Analyses
11Outgoing
9Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameVAV2
Key Genes/ProteinsRAC1, Vimentin, VIM, VIMENTIN, TNF-Α, TNF
Related DiseasesAutoimmune, Inflammation
Related PathwaysAutophagy, Apoptosis

Wiki Pages (10)

Knowledge base pages for this entity

EPHA7 Gene

gene · 3390 words

EPHA6 — Ephrin Type-A Receptor 6

gene · 3363 words

EPHA8 Gene

gene · 3199 words

EPHA3 Gene

gene · 3109 words

EPHA4 Gene

gene · 3062 words

Pathway Diagram

graph TD
    VAV2["VAV2"]
    VAV2 -->|"phosphorylates"| RAC1["RAC1"]
    VAV2 -->|"expressed in"| Autoimmune["Autoimmune"]
    VAV2 -->|"expressed in"| Inflammation["Inflammation"]
    VAV2 -->|"inhibits"| VIMENTIN["VIMENTIN"]
    VAV2 -->|"expressed in"| TNF__["TNF-Alpha"]
    VAV2 -->|"expressed in"| Autophagy["Autophagy"]
    VAV2 -->|"expressed in"| Apoptosis["Apoptosis"]
    VAV2 -->|"expressed in"| TNF["TNF"]
    Vimentin["Vimentin"] -->|"activates"| VAV2
    VIM["VIM"] -->|"activates"| VAV2
    INFLAMMATION["INFLAMMATION"] -->|"expressed in"| VAV2
    TNF -->|"expressed in"| VAV2
    APOPTOSIS["APOPTOSIS"] -->|"expressed in"| VAV2
    AUTOPHAGY["AUTOPHAGY"] -->|"expressed in"| VAV2
    RNA["RNA"] -->|"expressed in"| VAV2
    AND["AND"] -->|"activates"| VAV2

Outgoing (11)

TargetRelationTypeStr
RAC1phosphorylatesprotein0.85
Autoimmuneexpressed_indisease0.65
Inflammationexpressed_indisease0.65
VIMENTINinhibitsgene0.60
TNF-Αexpressed_ingene0.60

Incoming (9)

SourceRelationTypeStr
Vimentinactivatesprotein0.85
VIMactivatesgene0.85
INFLAMMATIONexpressed_ingene0.60
TNFexpressed_ingene0.60
APOPTOSISexpressed_ingene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found