concept

AUTOPHAGOSOME FORMATION

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about AUTOPHAGOSOME FORMATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

38Connections

0Hypotheses

4Analyses

3Outgoing

35Incoming

0Experiments

5Debates

No summary available yet.

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💡 Concept Info

Name	AUTOPHAGOSOME FORMATION

Pathway Diagram

graph TD
    AUTOPHAGOSOME_FORMATION["AUTOPHAGOSOME FORMATION"]
    AUTOPHAGOSOME_FORMATION -->|"involved_in"| ER_Mitochondria_Contact_Site["ER-Mitochondria Contact Site"]
    AUTOPHAGOSOME_FORMATION -->|"component_of"| Autophagy["Autophagy"]
    Autophagy -->|"involved_in"| AUTOPHAGOSOME_FORMATION
    ER_Mitochondria_Contact_Sites["ER-Mitochondria Contact Sites"] -->|"involved_in"| AUTOPHAGOSOME_FORMATION
    BECN1_PIK3C3_Complex["BECN1-PIK3C3 Complex"] -->|"involved_in"| AUTOPHAGOSOME_FORMATION
    Isolation_Membranes["Isolation Membranes"] -->|"involved_in"| AUTOPHAGOSOME_FORMATION
    LC3["LC3"] -->|"mediates"| AUTOPHAGOSOME_FORMATION
    MAP1LC3_Lipidation["MAP1LC3 Lipidation"] -->|"contributes to"| AUTOPHAGOSOME_FORMATION
    BECN1["BECN1"] -->|"involved_in"| AUTOPHAGOSOME_FORMATION

Outgoing (3)

Target	Relation	Type	Str
ER-Mitochondria Contact Site	involved_in	mechanism	0.95
Autophagy	component_of	process	0.90
ATG	associated_with	protein	0.90

Incoming (35)

Source	Relation	Type	Str
ER-mitochondria contact site	mediates	process	0.96
ER-Mitochondria Contact Sites	involved_in	organelle	0.95
Map1Lc3	involved_in	protein	0.95
Autophagy	involved_in	process	0.95
ATG14	involved_in	protein	0.93
ATG2A-G433A	inhibits	variant	0.92
ATG5	involved_in	protein	0.92
mitochondria-associated ER membrane	mediates	process	0.91
LC3B	biomarker_for	protein	0.90
LC3	regulates	protein	0.90
RAB7A	promotes	protein	0.90
ER-mitochondria contact sites	mediates	organelle	0.90
LC3	mediates	entity	0.90
BECN1-PIK3C3 Complex	involved_in	protein	0.90
MAP1LC3 Lipidation	contributes_to	process	0.90
SQSTM1	associated_with	protein	0.90
BECN1	activates	gene	0.90
BECN1	involved_in	gene	0.90
Isolation Membranes	involved_in	mechanism	0.90
ATG9A	involved_in	protein	0.85
ATG14	biomarker_for	protein	0.85
STX17	involved_in	protein	0.85
ACETYLATION	regulates	process	0.80
ER-mitochondria contact sites	promotes	organelle	0.80
LRRK2	regulates	protein	0.80
ULK1	activates	protein	0.70
ATG41	activates	protein	0.70
PI3P generation	activates	process	0.70
membrane lipid composition	modulates	mechanism	0.70
BECN1	regulates	gene	0.70
ATG9	activates	protein	0.70
LC3B	regulates	gene	0.70
MAP1LC3B	part_of	gene	0.70
membrane lipid composition	associated_with	pathway	0.70
ULK1 Ser555 phosphorylation inhibition	inhibits	phenotype	0.70