concept

CANCER PROGRESSION

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CANCER PROGRESSION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

43Connections

0Hypotheses

0Analyses

0Outgoing

43Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	CANCER PROGRESSION

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    CANCER_PROGRESSION["CANCER PROGRESSION"]
    LOX["LOX"] -->|"involved_in"| CANCER_PROGRESSION
    LOXL1["LOXL1"] -->|"involved_in"| CANCER_PROGRESSION
    LOXL2["LOXL2"] -->|"involved_in"| CANCER_PROGRESSION
    LOXL3["LOXL3"] -->|"involved_in"| CANCER_PROGRESSION
    LOXL4["LOXL4"] -->|"involved_in"| CANCER_PROGRESSION
    Complement_System["Complement System"] -->|"modulates"| CANCER_PROGRESSION
    MYC["MYC"] -->|"promotes"| CANCER_PROGRESSION
    EGFR_mutations["EGFR mutations"] -->|"causes"| CANCER_PROGRESSION

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (43)

Source	Relation	Type	Str
LOX	involved_in	gene	0.95
LOXL4	involved_in	gene	0.95
Stress Granules	associated_with	process	0.95
MYC	promotes	gene	0.95
LOX	promotes	gene	0.95
LOXL4	promotes	gene	0.95
ECM	promotes	process	0.95
LOXL1	involved_in	gene	0.95
LOXL2	involved_in	gene	0.95
LOXL3	involved_in	gene	0.95
Complement System	modulates	pathway	0.95
LOXL1	promotes	gene	0.95
LOXL2	promotes	gene	0.95
LOXL3	promotes	gene	0.95
EGFR mutations	causes	gene	0.90
EGFR overexpression	causes	gene	0.90
Cancer Cell Plasticity	promotes	process	0.90
Cancer Cell Plasticity	contributes_to	process	0.90
N6-Methyladenosine	mediates	compound	0.90
PI3K/Akt/mTOR Pathway	regulates	pathway	0.90
m6A modification	drives	process	0.90
Ferroptosis	associated_with	process	0.90
Metabolic Reprogramming	contributes_to	process	0.88
PSME2	associated_with	gene	0.88
Netrin-1 Inhibition	inhibits	mechanism	0.85
m6A Modification	involved_in	process	0.85
Intratumor Heterogeneity	promotes	phenotype	0.85
Intratumor Heterogeneity	associated_with	phenotype	0.85
Ecm Stiffness-Induced Oncogenic Signaling	mediates	mechanism	0.85
Efnb1-Ephb4	promotes	protein	0.85
Irinotecan	suppresses	drug	0.85
TFR1	promotes	protein	0.85
Senescence	contributes_to	process	0.85
Neuronal Targets	involved_in	biomarker	0.80
Fatty Liver Disease	risk_factor_for	disease	0.80
Liver Metabolic Dysfunction	contributes_to	phenotype	0.80
NTN1	promotes	protein	0.80
Hnrnpa2B1	contributes_to	protein	0.80
CD274	promotes	protein	0.80
NF-κB	promotes	pathway	0.75
autophagy	regulates	process	0.70
MAMs	contributes_to	process	0.70
Senescence	promotes	biological_process	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

CANCER PROGRESSION

Understanding Entity Pages

Wiki Pages (20)

HNRNPA2B1 Protein

CREB Signaling in Neurodegeneration

RASGRP1 Gene

UBE2V1 Gene (UEV-1)

Exosome Biogenesis in Neurodegeneration

Gamma-Synuclein Protein

Stress Granules in Neurodegeneration

PLAU Gene (Urokinase)

KIF26A — Kinesin Family Member 26A

RBM25 Protein

MEKK3 Protein

FZD8 Gene

FANCF Gene

eef1a1

TRIM3

EPHA10 Gene

MAP2K3 Protein (MEK3)

E2F4 Gene