Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FERRITINOPHAGY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | FERRITINOPHAGY |
| Key Genes/Proteins | NCOA4 |
Knowledge base pages for this entity
graph TD
FERRITINOPHAGY["FERRITINOPHAGY"]
FERRITINOPHAGY -->|"modulates"| iron_homeostasis["iron homeostasis"]
FERRITINOPHAGY -->|"promotes"| oxidative_stress["oxidative stress"]
FERRITINOPHAGY -->|"causes"| ferroptosis["ferroptosis"]
FERRITINOPHAGY -->|"contributes to"| Ferroptosis["Ferroptosis"]
FERRITINOPHAGY -->|"promotes"| reactive_oxygen_species_accumu["reactive oxygen species accumulation"]
FERRITINOPHAGY -->|"promotes"| inflammation["inflammation"]
NCOA4["NCOA4"] -->|"mediates"| FERRITINOPHAGY
ULK1["ULK1"] -->|"activates"| FERRITINOPHAGY
PI3K_AKT_MTOR["PI3K/AKT/MTOR"] -->|"regulates"| FERRITINOPHAGY
STAT3["STAT3"] -->|"regulates"| FERRITINOPHAGY
BECN1["BECN1"] -->|"regulates"| FERRITINOPHAGY| Target | Relation | Type | Str |
|---|---|---|---|
| iron homeostasis | modulates | process | 0.95 |
| oxidative stress | promotes | phenotype | 0.95 |
| ferroptosis | associated_with | pathway | 0.90 |
| ferroptosis | causes | phenotype | 0.90 |
| reactive oxygen species accumulation | promotes | phenotype | 0.90 |
| ferroptosis | promotes | process | 0.90 |
| Iron Homeostasis | regulates | pathway | 0.90 |
| Intracellular Iron | associated_with | compound | 0.90 |
| Ferroptosis | contributes_to | process | 0.90 |
| inflammation | promotes | process | 0.90 |
| Ferroptosis | modulates | process | 0.90 |
| organ injury | causes | phenotype | 0.85 |
| Ferroptosis | involved_in | process | 0.85 |
| Autophagy | involved_in | process | 0.85 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||