Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HIPPOCAMPAL NEUROGENESIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Name | HIPPOCAMPAL NEUROGENESIS |
| Linked Hypotheses | 4 hypotheses |
Knowledge base pages for this entity
graph TD
HIPPOCAMPAL_NEUROGENESIS["HIPPOCAMPAL NEUROGENESIS"]
HIPPOCAMPAL_NEUROGENESIS -.protects against.-> Alzheimer_s_disease["Alzheimer's disease"]
CHI3L1["CHI3L1"] -->|"inhibits"| HIPPOCAMPAL_NEUROGENESIS
CTNNB1["CTNNB1"] -->|"involved_in"| HIPPOCAMPAL_NEUROGENESIS
Autoimmune_Mediated_Neuroinfla["Autoimmune-Mediated Neuroinflammation"] -->|"contributes to"| HIPPOCAMPAL_NEUROGENESIS
ATG5["ATG5"] -->|"regulates"| HIPPOCAMPAL_NEUROGENESIS
Microglia["Microglia"] -->|"modulates"| HIPPOCAMPAL_NEUROGENESIS
Omega_3_Polyunsaturated_Fatty_["Omega-3 Polyunsaturated Fatty Acids"] -.protects against.-> HIPPOCAMPAL_NEUROGENESIS
microglia["microglia"] -->|"regulates"| HIPPOCAMPAL_NEUROGENESIS
exercise["exercise"] -->|"activates"| HIPPOCAMPAL_NEUROGENESIS| Target | Relation | Type | Str |
|---|---|---|---|
| Memory Consolidation | involved_in | process | 0.90 |
| Alzheimer Disease | associated_with | disease | 0.90 |
| Alzheimer's disease | protects_against | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CHI3L1 | inhibits | protein | 0.95 |
| High-Fat Diet | inhibits | drug | 0.95 |
| CTNNB1 | involved_in | protein | 0.90 |
| Autoimmune-Mediated Neuroinflammation | contributes_to | disease | 0.90 |
| ATG5 | regulates | gene | 0.90 |
| BDNF | promotes | gene | 0.90 |
| Obesity | associated_with | disease | 0.90 |
| BDNF | associated_with | protein | 0.85 |
| Microglia | modulates | cell_type | 0.85 |
| Lipid Mediators | associated_with | compound | 0.80 |
| Omega-3 Polyunsaturated Fatty Acids | protects_against | compound | 0.80 |
| TNF | regulates | protein | 0.80 |
| TNF | involved_in | protein | 0.75 |
| exercise | activates | process | 0.70 |
| Chinese herbal medicine | activates | drug | 0.70 |
| TREM2 | promotes | gene | 0.70 |
| microglia | regulates | cell_type | 0.70 |
| MCT8 | involved_in | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||