gene 1,168 words KG: BID 2026-03-27
kind:genesection:genesstate:published
Contents

BID — BH3 Interacting Domain Death Agonist

🧬 Gene Info
Gene SymbolBID
Full NameBH3 Interacting Domain Death Agonist
Chromosome22q11.21
Protein FamilyBCL2 family, BH3-only proteins
Functionis a relatively inactive cytosolic protein.
Molecular Weight22 kDa
Amino Acids195 aa
PathwaysApoptosis, Stem Cell
UniProt IDP55957
NCBI Gene ID637
Ensembl IDENSG00000105619
OMIM603678
GeneCardsBID
Human Protein AtlasBID
N-terminal regionContains caspase-8 cleavage sites (D75, D81)
Associated DiseasesALS, Aging, Alzheimer, Inflammation, Neurodegeneration
InteractionsMTOR, BAD, AKT, BAX, CYP2D6, CYP3A4
KG Connections355 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

BID associated_with BAD
BID associated_with BAK1
BID associated_with BAX
BID activates MTOR
BID associated_with LAMP2
BID therapeutic_target TLR2
BID associated_with PPP1CB
BID activates BAD
BID therapeutic_target AKT
BID therapeutic_target MTOR