gene 991 words KG: AIF1
Contents

AIF1 Gene

🧬 Gene Info
Gene SymbolAIF1
Functionencodes a calcium-binding cytoskeletal adaptor that is strongly enriched in microglia.
PathwaysAutophagy, Inflammasome, Mitophagy, Neuroinflammatory
Ensembl IDENSG00000240065
GeneCardsAIF1
Human Protein AtlasAIF1
Associated DiseasesAging, Als, Alzheimer
Known Drugs/Compoundsrapamycin
InteractionsACTB, AGING, AMPK, AND, ARC, ASC
KG Connections391 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (2)

Epigenetic Silencing of AIF1 Gene Locus by Chronic Inflammat
Score: 0.64
Circulating IBA1 Protein Absorption/Interference with Detect
Score: 0.51

Knowledge Graph (12 edges)

ACTB associated_with AIF1
IL1B inhibits AIF1
IL6 inhibits AIF1
CASP1 associated_with AIF1
ATG5 associated_with AIF1
GFAP associated_with AIF1
SNCA inhibits AIF1
BECN1 associated_with AIF1
AIF1 associated_with ATG7
AIF1 inhibits ASC

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