gene 908 words KG: BAK1
Contents

BAK1 Gene

🧬 Gene Info
Gene SymbolBAK1
Full NameBCL2-Antagonist/Killer 1
Chromosome6p21.31
Protein TypeBCL2 family (pro-apoptotic)
FunctionBAK1 is a 25 kDa protein localized primarily to the mitochondrial outer membrane
Molecular Weight25 kDa
PathwaysFerroptosis, Mtor, Necroptosis, Pyroptosis, apoptosis
UniProt IDQ9YM15
NCBI Gene ID578
Ensembl IDENSG00000130165
GeneCardsBAK1
Human Protein AtlasBAK1
Mitochondrial DynamicsRegulation of mitochondrial fission and fusion
Associated DiseasesAls, oxidative stress, OXIDATIVE_STRESS, Tumor
InteractionsAMBRA1, ATP, BAX, BCL2, BECN1, BNIP3
KG Connections146 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Apoptosis-Senescence Decision Point Intervention
Score: 0.65

Knowledge Graph (12 edges)

FAS regulates BAK1
MMP1 regulates BAK1
BAK1 biomarker_for BCL2L1
BID associated_with BAK1
BAK1 associated_with BAX
BAK1 activates MTOR
BCL2L1 biomarker_for BAK1
MTOR activates BAK1
BAX associated_with BAK1
BAK1 regulates FAS

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