| Gene Symbol | FAS |
| Protein Family | TNF receptor superfamily |
| Protein Type | Receptor |
| Function | FAS (also known as CD95 or APO-1) is a cell surface receptor that triggers apoptosis upon binding with its ligand FASLG |
| Primary Expression | neurons and glial cells throughout the brain and plays roles in developmental apoptosis, immune surveillance, synaptic pruning, a |
| Subcellular Localization | Plasma membrane |
| Molecular Weight | 43 kDa |
| Pathways | pathway:
### Activation Cascade |
| UniProt ID | P01375 |
| GeneCards | FAS |
| Human Protein Atlas | FAS |
| Associated Diseases | AD, ALS, AMI, Alzheimer, Alzheimer's disease |
| Interactions | TNF, LMNA, APH1B, APOE, IL6, SREBF1 |
| KG Connections | 605 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |