gene 696 words KG: CARD14
Contents

Caspase Recruitment Domain Family Member 14

🧬 Gene Info
Gene SymbolCARD14
Chromosome2q31.1
Functionis a gene encoding a member of the CARD family of that play critical roles in regulating cell death, inflammation, and immune signaling pathways[@jordan2012].
Primary Expressionskin keratinocytes and immune cells, but also shows expression in various tissues including the brain[@chang2018]
Molecular Weight125 kDa
PathwaysNF-κB, NF-κB signaling
UniProt IDQ9Y2K7
NCBI Gene ID15292
Ensembl IDENSG00000100916
GeneCardsCARD14
Human Protein AtlasCARD14
Associated Diseasesneurodegeneration
InteractionsAND, BCL2, MITOPHAGY, MYC, NF-ΚB, PLIN4
KG Connections20 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

TAU protects_against CARD14
FGF2 protects_against CARD14
PLIN4 inhibits CARD14
BDNF protects_against CARD14
BCL2 inhibits CARD14
CARD14 protects_against APP
CARD14 activates MYC
MITOPHAGY inhibits CARD14
NEURODEGENERATION protects_against CARD14
ALZHEIMER protects_against CARD14

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