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cell 737 words KG: TPH2 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

Dorsal Raphe Nucleus Expanded (DRN)

🧫 Cell Type Info
Cell TypeDorsal Raphe Nucleus Expanded (DRN)
Also Known AsTryptophan Hydroxylase 2
Key PathwaysMapk, Oxidative Stress
Associated DiseasesALS, Als, Bipolar, Depression, Ms, Multiple Sclerosis
Linked Hypotheses17 hypotheses

Knowledge Graph

Related Hypotheses (7)

Purinergic Signaling Polarization Control
Score: 0.55Mechanosensitive Ion Channel Reprogramming
Score: 0.51Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57Senescent Cell Mitochondrial DNA Release
Score: 0.54

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedSenolytic therapy for age-related neurodegeneration
neurodegeneration · archivedCell type vulnerability in Alzheimer's Disease (SEA-AD data)
neurodegeneration · failedCell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived

See Also (15)

ALS Therapeutic Landscape — Programs by Phase and Modal
disease · Pages share 3 hypothesesWnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypothesesWNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypothesesvip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 3 hypothesesVEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 3 hypotheses

Knowledge Graph (12 edges)

TPH2 associated_with GABRA5
TPH2 associated_with POLG
TPH2 associated_with TRPM2
TPH2 associated_with GRM3
TPH2 expressed_in KCNK2
TPH2 regulates CCL3
TPH2 activates NGF
TPH2 activates IDO1
TPH2 activates GBA
TPH2 associated_with DRD1
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