gene 1,963 words KG: DAO 2026-03-25
kind:genesection:genesstate:published
Contents

DAO Gene

🧬 Gene Info
Gene SymbolDAO
Full NameD-Amino Acid Oxidase
Chromosome12q24.11
Protein TypeEnzyme
Functionencodes a flavin adenine dinucleotide (FAD)-dependent enzyme that catalyzes the oxidative deamination of D-amino acids.
Primary ExpressionBrain (neurons, astrocytes), liver, kidney
Molecular Weight39 kDa
Amino Acids347 aa
UniProt IDP14920
NCBI Gene ID1680
Ensembl IDENSG00000110888
OMIM124050
GeneCardsDAO
Human Protein AtlasDAO
Protein ClassFlavoenzyme, Peroxisomal enzyme
Associated DiseasesALS, Bipolar, Depression, Ms, Schizophrenia
InteractionsDISC1, GRIN2B, GRM3, GRM4, NCAM1, NRG1
KG Connections92 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.48
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

PS-NMP shape-dependent colonic barrier damage in mice
validation · proposed · Score: 0.95

See Also (9)

Packard Center for ALS Research
institution · KG edge: associated_with
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: associated_with
GABRA5 Gene
gene · KG edge: associated_with
DRD1 Gene
gene · KG edge: associated_with
DISC1 — Disrupted in Schizophrenia 1
gene · KG edge: associated_with

Knowledge Graph (12 edges)

DAO associated_with BMAL1
DAO associated_with GRM4
DAO associated_with SYNGR1
DAO associated_with BDNF
DAO associated_with NCAM1
DAO associated_with RGS4
DAO associated_with GRIN2B
DAO associated_with DRD1
DAO associated_with TPH2
DAO associated_with GABRA5