cell 689 words KG: ent-gene-87417b6d 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

GABA-A Gamma2 Neurons

🔬 Protein Info
Gene SymbolGABA
Full NameA Gamma2 Neurons
Chromosome12p12.3
Protein TypeCell Type
Functionis a hallmark of neurodegeneration.
Primary Expressionhippocampus, cortex, cerebellum, thalamus, hypothalamus
Amino Acids602 aa
Exons14
PathwaysGABAergic Signaling
GeneCardsGABA
Human Protein AtlasGABA
Associated DiseasesALS, ALZHEIMER'S DISEASE, Alzheimer
Known Drugs/Compoundsrapamycin
InteractionsATG, MTOR, RB1CC1, JNK, MAVS, HUNTINGTON
KG Connections1323 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (5)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.38
Age-Dependent Complement C4b Upregulation Drives Synaptic Vu
Score: 0.47

Related Analyses (12)

Metabolomic signatures of neurodegeneration and energy metab
neurodegeneration · failed
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between neurons and glia
neurodegeneration · archived

Related Experiments (7)

Metabolic Pathway-Targeted Therapy in ALS
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
Non-Dopaminergic Neurotransmitter Degeneration in PD - Exper
clinical · proposed · Score: 0.40
Clinical characterization of GABRA1/GABRG2 microdeletion pat
clinical · proposed · Score: 0.95

Knowledge Graph (2 edges)

ent-gene-87417b6d data_in benchmark_ot_ad_answer_key:GABRG2
benchmark_ot_ad_answer_key:GABRG2 data_in ent-gene-87417b6d