| Gene Symbol | LRRK2 |
| Full Name | Associated Dopamine Neurons |
| Chromosome | 12q12 |
| Protein Type | Protein |
| Amino Acids | 2527 aa |
| Pathways | MAPK |
| UniProt ID | Search UniProt |
| GeneCards | LRRK2 |
| Human Protein Atlas | LRRK2 |
| Category | Disease-Specific Neurons |
| Location | Substantia nigra pars compacta (SNc), Ventral Tegmental Area (VTA) |
| Cell Types | Dopaminergic neurons (A9 population) |
| Primary Neurotransmitter | Dopamine |
| Key Markers | TH (Tyrosine Hydroxylase), DAT, LRRK2, G2019S mutation |
| Associated Disease | Parkinson's Disease (LRRK2-associated PD) |
| Associated Diseases | ALS, Aging, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis |
| Known Drugs/Compounds | RAPAMYCIN, levodopa, Cigarette Smoking, BIIB094, VALPROIC ACID, rapamycin |
| Interactions | ATG16L1, RB1CC1, GABARAP, ERN1, STAT3, IFNG |
| KG Connections | 2480 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |