cell 593 words KG: oligodendrocytes 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

Oligodendrocytes in Multiple System Atrophy

🧫 Cell Type Info
Cell Typeoligodendrocytes
Definition<table class="infobox infobox-cell">
Key MarkersTAU, myelin, HSPA1A, SMS2, GPR37, PIEZO1, GBA1, Prosaposin
Key PathwaysDna Damage Response, sphingolipid metabolism, complement cascade, pyroptosis, unfolded protein response
Associated DiseasesAlzheimer's Disease, Parkinson's Disease, aging, Alzheimer's disease, Alzheimer'S Disease, Vascular Dementia
Linked Hypotheses114 hypotheses

Knowledge Graph

Related Hypotheses (30)

Microbiota-Microglia Axis Modulation
Score: 0.48
Perinatal Immune Challenge Prevention
Score: 0.42
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.59

Related Analyses (23)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived

See Also (4)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
ABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

oligodendrocytes activates neuroinflammation
oligodendrocytes activates neurodegeneration
oligodendrocytes produces myelin
oligodendrocytes involved_in myelin dysfunction
oligodendrocytes activates multiple sclerosis
oligodendrocytes interacts_with multiple sclerosis
oligodendrocytes causes Parkinson's disease
oligodendrocytes causes neurodegeneration
oligodendrocytes causes neuroinflammation
oligodendrocytes activates Parkinson's disease