gene 1,538 words KG: ent-gene-8df81d7c 2026-03-29
kind:genesection:entitiesstate:publishedevidence:strong
Contents

PARK2 — Parkin Gene Entity Page

🧬 Gene Info
Gene SymbolPARK2
Full NameParkin RBR E3 Ubiquitin Protein Ligase
Chromosome6q26
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionSubstantia nigra, Striatum, Hippocampus, Cortex, Heart
Molecular Weight52 kDa
Amino Acids465 aa
Exons12
PathwaysApoptosis, Immune Response, Mitophagy
UniProt IDO60260
NCBI Gene ID5071
Ensembl IDENSG00000185345
OMIM602544
GeneCardsPARK2
Human Protein AtlasPARK2
Associated DiseasesALS, Aging, Alzheimer, Alzheimer's disease, Cancer
Known Drugs/CompoundsTHSG, levodopa
InteractionsMAP1LC3B, PINK1, ATG5, LC3, TIMM17A, EIF2A
KG Connections502 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph