gene 2,416 words KG: FANCE
Contents

FANCE Gene

🧬 Gene Info
Gene SymbolFANCE
Chromosome6p21.31
Protein TypeAdaptor Protein
Functionencodes an essential adaptor protein that plays a critical role in the Fanconi anemia (FA) DNA repair pathway.
Molecular Weight44 kDa
Amino Acids396 aa
Ensembl IDENSG00000112039
GeneCardsFANCE
Human Protein AtlasFANCE
Human-Mouse85% identical at the amino acid level
Human-Zebrafish72% identical
DrosophilaPartial ortholog with 45% identity
YeastNo clear ortholog (FA pathway is metazoan-specific)
Associated Diseasesneurodegeneration
InteractionsATM, ATR, DNA, FANCA, FANCC, FANCI
KG Connections24 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

FANCC interacts_with FANCE
ATM interacts_with FANCE
FANCA interacts_with FANCE
FANCE contributes_to AIM2
FANCE interacts_with ATR
ATR interacts_with FANCE
AIM2 contributes_to FANCE
FANCE interacts_with FANCA
APOPTOSIS contributes_to FANCE
DNA interacts_with FANCE

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