Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FZR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | FZR1 |
| Key Genes/Proteins | CDH1, Anapc11, UBIQUITIN, JUN, AND, CDK2 |
| Related Diseases | Cancer, ALS, Als |
| Related Pathways | Cell Cycle |
graph TD
FZR1["FZR1"]
FZR1 -->|"encodes"| CDH1["CDH1"]
FZR1 -->|"activates"| Cancer["Cancer"]
FZR1 -->|"activates"| ALS["ALS"]
FZR1 -->|"activates"| Als["Als"]
FZR1 -->|"activates"| UBIQUITIN["UBIQUITIN"]
FZR1 -->|"activates"| JUN["JUN"]
FZR1 -->|"activates"| AND["AND"]
APC["APC"] -->|"activates"| FZR1
DNA["DNA"] -->|"activates"| FZR1
CDK2["CDK2"] -->|"activates"| FZR1
UBIQUITIN -->|"activates"| FZR1
CDH1 -->|"activates"| FZR1
JUN -->|"activates"| FZR1| Target | Relation | Type | Str |
|---|---|---|---|
| CDH1 | encodes | protein | 0.95 |
| Anapc11 | interacts_with | protein | 0.85 |
| Cancer | activates | disease | 0.65 |
| ALS | activates | disease | 0.65 |
| Als | activates | disease | 0.65 |
| UBIQUITIN | activates | gene | 0.60 |
| JUN | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| CDH1 | activates | gene | 0.60 |
| CDK2 | activates | gene | 0.60 |
| CANCER | activates | gene | 0.60 |
| Cell Cycle | activates | pathway | 0.60 |
| T Cell | activates | cell_type | 0.60 |
| DNA | activates | gene | 0.60 |
| APC | activates | gene | 0.60 |
| Actin | activates | protein | 0.60 |
| Rb | activates | protein | 0.60 |
| Erk | activates | protein | 0.60 |
| App | activates | protein | 0.60 |
| ubiquitin-proteasome | participates_in | pathway | 0.60 |
| T Cell | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||