gene 1,481 words KG: CSF1R
Contents

CSF1R — Colony Stimulating Factor 1 Receptor

🧬 Gene Info
Gene SymbolCSF1R
Full NameColony Stimulating Factor 1 Receptor
Chromosome5q32
Protein TypeReceptor
FunctionUpon ligand binding, CSF1R undergoes
Primary ExpressionMicroglia, Macrophages, Osteoclasts, Placenta
Molecular Weight107.6 kDa
Amino Acids972 aa
PathwaysPI3K
UniProt IDP07333
NCBI Gene ID1436
Ensembl IDENSG00000182578
OMIM164770
GeneCardsCSF1R
Human Protein AtlasCSF1R
Associated DiseasesAls, Alzheimer, Anxiety, Atherosclerosis, cancer
Known Drugs/Compoundsdasatinib, KETAMINE, nicotinamide, NICOTINAMIDE, PLX3397, PLX5622
InteractionsABL1, ABL2, ACHE, ACT001, Actin, AD
SciDEX HypothesesTREM2-Independent Microglial Activation via CSF1R
CSF1R Inhibition-Mediated Microglial Replacement a
CSF1R Agonism for TREM2-Independent Microglial Act (+1 more)
KG Connections704 knowledge graph edges
DatabasesGeneCardsHPASTRING

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