gene 2,670 words KG: RHOA
Contents

RHOA Gene — Ras Homolog Family Member A

🧬 Gene Info
Gene SymbolRHOA
Full NameRas Homolog Family Member A
Chromosome3p21.31
Functionencodes a small GTP-binding protein that functions as a molecular switch, cycling between an active GTP-bound state and an inactive GDP-bound state.
Molecular Weight~22 kDa
Amino Acids191 aa
PathwaysAkt, Angiogenesis, Apoptosis, Complement, Egfr Signaling
UniProt ID[P61586](https://www.uniprot.org/uniprotkb/P61586/entry)
Ensembl IDENSG00000167553
GeneCardsRHOA
Human Protein AtlasRHOA
Associated DiseasesAlzheimer, cancer, Dementia, Lung Cancer, Ms, neurodevelopmental disorders
InteractionsACVR1, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AMYLOID-BETA
SciDEX HypothesesComplement-Independent SPP1 Signaling Disruption
KG Connections354 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Complement-Independent SPP1 Signaling Disruption
Score: 0.00

Knowledge Graph (12 edges)

EPHB4 activates RHOA
RHOA inhibits ARF1
ARF1 inhibits RHOA
P62 regulates RHOA
ROCK1 activates RHOA
LAMP1 regulates RHOA
SQSTM1 regulates RHOA
RHOA regulates TFEB
RHOA regulates APP
RHOA regulates SQSTM1

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