gene 1,385 words KG: CNR2
Contents

CNR2 Gene - Cannabinoid Receptor 2 (CB2)

🧬 Gene Info
Gene SymbolCNR2
Full NameCannabinoid Receptor Type 2
Chromosome1p36.12
Functionis a component of the endocannabinoid system, a neuromodulatory system involved in various physiological processes including pain sensation, immune response, and neuroinflammation.
Primary Expressionimmune cells and peripheral tissues
Molecular Weight~40 kDa
Amino Acids360 aa
PathwaysMAPK pathway, PI3K
UniProt IDP47972
NCBI Gene ID1269
Ensembl IDENSG00000188322
OMIM605026
GeneCardsCNR2
Human Protein AtlasCNR2
Alternative NamesCB2, CNR2, CX5, GPR18, CB2R
Associated DiseasesALS, Alzheimer
InteractionsCCR5, CXCL8, C3AR1, GRM2, CXCL12, MTNR1A
KG Connections52 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (1)

Circadian Glymphatic Rescue Therapy (Melatonin-focused)
Score: 0.55

Related Analyses (2)

Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

CB2R deletion effects on GVHD-induced behavioral changes
validation · proposed · Score: 0.90
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs
clinical · proposed · Score: 0.90
Circadian-Vascular-Metabolic Syndrome (CVMS) Intervention Tr
clinical · proposed · Score: 0.40
DLB Cognitive Fluctuation Mechanism Experiment
clinical · proposed · Score: 0.40

See Also (9)

Packard Center for ALS Research
institution · KG edge: interacts_with
Alzheimer Indonesia
institution · KG edge: activates
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: expressed_in
GRM2 Gene
gene · KG edge: associated_with
cxcl8
gene · KG edge: associated_with

Knowledge Graph (12 edges)

CNR2 associated_with C3AR1
CNR2 associated_with ADCY2
CNR2 associated_with GRM2
CNR2 associated_with CXCL12
CNR2 interacts_with CCR5
CNR2 interacts_with CXCL8
CNR2 interacts_with C3AR1
CNR2 interacts_with GRM2
CNR2 interacts_with CXCL12
CNR2 associated_with CCR5