gene 1,887 words KG: GRM2 2026-03-23
kind:genesection:genesstate:published
Contents

GRM2 Gene

🧬 Gene Info
Gene SymbolGRM2
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionBrainstem, Amygdala, Cortex, Hippocampus, Cerebellum
PathwaysWnt, Oxidative Phosphorylation
Ensembl IDENSG00000164082
GeneCardsGRM2
Human Protein AtlasGRM2
Associated DiseasesALS, Alzheimer, Inflammation, Neuroinflammation, Ptsd
InteractionsWNT1, IL13, WNT11, TNFRSF1B, TNFRSF13C, CXCL12
KG Connections109 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Epigenetic Memory Erasure via TET2 Activation
Score: 0.52
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.47
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.41

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Packard Center for ALS Research
institution · KG edge: activates
Alzheimer Indonesia
institution · KG edge: interacts_with
CXCL12 Gene
gene · KG edge: associated_with
CRH Gene
gene · KG edge: expressed_in
CNR2 Gene - Cannabinoid Receptor 2 (CB2)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

GRM2 associated_with NPY
GRM2 associated_with CXCL8
GRM2 associated_with CCR5
GRM2 associated_with MTNR1A
GRM2 associated_with CNR2
GRM2 associated_with C3AR1
GRM2 activates WNT1
GRM2 expressed_in CRH
GRM2 expressed_in ADRA2B
GRM2 activates IL13