gene 2,002 words KG: ADRA1D 2026-03-29
section:geneskind:genetopic:alzheimerstopic:parkinsons
Contents

ADRA1D Gene

🧬 Gene Info
Gene SymbolADRA1D
Full NameAlpha-1D Adrenergic Receptor
Chromosome19p13
Primary Expressionthe cerebral cortex, hippocampus, thalamus, hypothalamus, and vascular smooth muscle, where it mediates diverse physiological responses
Molecular Weight~60 kDa
Amino Acids560 aa
Exons2
PathwaysAutophagy, IMMUNE RESPONSE
UniProt IDP25100
NCBI Gene ID146
Ensembl IDENSG00000160040
OMIM104221
GeneCardsADRA1D
Human Protein AtlasADRA1D
Gene Length~4.5 kb
Associated DiseasesAlzheimer's disease, Parkinson's disease
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

APOE-Dependent Autophagy Restoration
Score: 0.61
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.44

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Actin Cytoskeleton Dynamics in Neurodegeneration
mechanism · KG edge: regulates
MYH2 Gene
gene · KG edge: regulates
MERTK - MER Tyrosine Kinase
gene · KG edge: regulates
LITAF — Lipopolysaccharide-Induced Tumor Necrosis Facto
gene · KG edge: regulates
JUN Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

ADRA1D provides_data_for ds-83b31ef18d49
ADRA1D regulates PDK4
ADRA1D regulates LITAF
ADRA1D regulates IL6R
ADRA1D regulates MERTK
ADRA1D regulates DUSP1
ADRA1D regulates ADCY9
ADRA1D regulates SOX2
ADRA1D regulates CDKN1A
ADRA1D regulates SESN1