gene 4,040 words KG: ATP5F1
Contents

ATP5F1 — ATP Synthase F1 Subunit Beta

🧬 Gene Info
Gene SymbolATP5F1
Full NameATP Synthase F1 Subunit Beta
Chromosome1p13.3
Functionencodes the beta subunit of the F1 catalytic sector of mitochondrial ATP synthase, also known as Complex V of the electron transport chain[@nature2010]
Primary ExpressionBrain, Heart, Muscle
Amino Acids511 aa
UniProt IDP06576
NCBI Gene ID547
Ensembl IDENSG00000067715
GeneCardsATP5F1
Human Protein AtlasATP5F1
InteractionsLMNA, CLOCK, SDHB, PPARG, PARK7, BACE1
KG Connections20 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (9)

Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.38
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.48
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Circadian Clock-Autophagy Synchronization
Score: 0.55
Temporal Decoupling via Circadian Clock Reset
Score: 0.52

Related Analyses (3)

Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived

Related Experiments (1)

Synaptic Mitochondrial Resilience Enhancement for Parkinson'
validation · proposed · Score: 0.40

See Also (15)

huntington-disease-treatment
therapeutic · KG edge: interacts_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: interacts_with
Packard Center for ALS Research
institution · KG edge: interacts_with
Alzheimer Indonesia
institution · KG edge: interacts_with
SIRT3 - Sirtuin 3
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

ATP5F1 interacts_with LMNA
ATP5F1 interacts_with CLOCK
ATP5F1 interacts_with SDHB
ATP5F1 interacts_with PPARG
ATP5F1 interacts_with PARK7
ATP5F1 interacts_with BACE1
ATP5F1 interacts_with P53
ATP5F1 interacts_with HUNTINGTON'S DISEASE
ATP5F1 interacts_with AMPK
ATP5F1 interacts_with ACETYL-COA