gene 2,016 words KG: CASP2 2026-03-21
kind:genesection:genesstate:published
Contents

CASP2 Gene

🧬 Gene Info
Gene SymbolCASP2
Full NameCaspase 2 (CASP2)
Chromosome7q34
Protein TypeProtein
FunctionCaspase 2 has diverse cellular functions beyond apoptosis:
Molecular Weight20 kDa
Amino Acids165 aa
PathwaysCell Cycle, Dna Repair, Oxidative Stress
UniProt IDSearch UniProt
Ensembl IDENSG00000106144
GeneCardsCASP2
Human Protein AtlasCASP2
Associated DiseasesAging, Cancer, Inflammation, Neurodegeneration
InteractionsUBIQUITIN, AUTOPHAGY, APOPTOSIS
KG Connections36 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
PARP1 Inhibition Therapy
Score: 0.58
Cryptic Exon Silencing Restoration
Score: 0.46
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Cross-Seeding Prevention Strategy
Score: 0.45

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: participates_in
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: implicated_in
Packard Center for ALS Research
institution · KG edge: activates
casp3
gene · KG edge: associated_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: causes

Knowledge Graph (12 edges)

CASP2 encodes CASPASE2
CASP2 associated_with CASP3
CASP2 interacts_with UBIQUITIN
CASP2 regulates NEURODEGENERATIVE DISEASES
CASP2 implicated_in INFLAMMATION
CASP2 causes DNA
CASP2 regulates Als
CASP2 implicated_in Inflammation
CASP2 implicated_in Apoptosis
CASP2 expressed_in Proteasome