| Gene Symbol | ATF3 |
| Full Name | Activating Transcription Factor 3 |
| Chromosome | 1q32.3 |
| Protein Type | Transcription Factor |
| Pathways | Apoptosis, Cholesterol, Epigenetic, Innate Immunity, Oxidative Stress |
| UniProt ID | Q9Y2T3 |
| NCBI Gene ID | 10566 |
| Ensembl ID | ENSG00000162771 |
| OMIM | 603148 |
| GeneCards | ATF3 |
| Human Protein Atlas | ATF3 |
| Stress-responsive transcription factor | Rapidly induced by cellular stress within 30-60 minutes |
| Adaptive response gene | Promotes cell survival or death depending on context and intensity |
| Transcriptional regulator | Binds to ATF/CRE sites in target gene promoters |
| Immediate-early gene | Induced by cAMP, calcium, and growth factors |
| Associated Diseases | Aging, Als, Alzheimer, Cardiovascular, Senescence |
| Interactions | AKT, AND, ANG, ANXA2, APOPTOSIS, ASC |
| KG Connections | 356 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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