| Gene Symbol | CKB |
| Function | Creatine kinase catalyzes the reversible transfer of a phosphate group from phosphocreatine to ADP |
| Pathways | Circadian Rhythm, Apoptosis |
| UniProt ID | P12277 |
| Ensembl ID | ENSG00000136053 |
| GeneCards | CKB |
| Human Protein Atlas | CKB |
| Energy Buffering | Maintains ATP levels during periods of high demand or stress |
| Energy Shuttle | PCr serves as a spatial energy shuttle from mitochondria to cytosol |
| Neuroprotection | Supports neuronal survival under metabolic stress |
| Synaptic Function | Provides energy for synaptic vesicle cycling and ion pump function |
| Oxidative Stress Protection | Reduces ROS production by maintaining mitochondrial function |
| Associated Diseases | ALS, Diabetes, Stroke |
| Interactions | BMAL1, BCL2, ARNT, HNRNPK, HSPD1, PRDX6 |
| KG Connections | 65 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |