gene 627 words KG: CREB3 2026-03-12
kind:genesection:genesstate:published
Contents

CREB3 Gene

🧬 Gene Info
Gene SymbolCREB3
Full NamecAMP Responsive Element Binding Protein 3
Chromosome9p13.3
Protein FamilyBasic Leucine Zipper (bZIP) Transcription Factors
Protein TypeTranscription Factor
FunctionCREB3 is a transcription factor with several functions
PathwaysEr Stress, Innate Immunity, Mitophagy
UniProt IDQ9Y241
NCBI Gene ID10488
Ensembl IDENSG00000105197
OMIM606443
GeneCardsCREB3
Human Protein AtlasCREB3
Associated DiseasesAging, Als, Cardiovascular, Ms
KG Connections41 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Mitophagy Receptor Pathway in Neurodegeneration
mechanism · KG edge: regulates
MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: contributes_to
ER Stress and Unfolded Protein Response in Corticobasal
mechanism · KG edge: regulates
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with

Knowledge Graph (12 edges)

CREB3 regulates PARKIN
CREB3 regulates UBIQUITIN
CREB3 regulates PARK6
CREB3 contributes_to MAPK8
CREB3 contributes_to NFKBIA
CREB3 regulates GFAP
CREB3 regulates PINK1
CREB3 contributes_to ATP1A1
CREB3 contributes_to PRDX6
CREB3 contributes_to YWHAZ